BindingDB PrimarySearch

Prostaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Malakand

Curated by ChEMBL

BDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)

IC50: 250nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...More data for this Ligand-Target Pair

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PDB NCI pathway Reactome pathway KEGG
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)

IC50: 280nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

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Prostaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Malakand

Curated by ChEMBL

BDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)

IC50: 480nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)

IC50: 630nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

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Details Article PubMed DrugBank

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558938(CHEMBL4797337)

IC50: 810nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558934(CHEMBL4754218)

IC50: 860nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558934(CHEMBL4754218)

IC50: 980nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558936(CHEMBL4794507)

IC50: 2.10E+3nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558937(CHEMBL4779865)

IC50: 4.23E+3nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558936(CHEMBL4794507)

IC50: 4.74E+3nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558937(CHEMBL4779865)

IC50: 5.29E+3nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM50242322(CHEMBL4066113)

IC50: 5.40E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558935(CHEMBL4742170)

IC50: 6.29E+3nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM50242315(CHEMBL4093688)

IC50: 6.50E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair

Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM50242323(CHEMBL4070917)

Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)

IC50: 8.00E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair

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Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM50242317(CHEMBL4085938)

IC50: 8.40E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair

Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM50242322(CHEMBL4066113)

IC50: 8.60E+3nMAssay Description:Inhibition of horse serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558938(CHEMBL4797337)

IC50: 8.94E+3nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM50242315(CHEMBL4093688)

IC50: 9.30E+3nMAssay Description:Inhibition of horse serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)

IC50: 1.01E+4nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

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Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM50242318(CHEMBL4098012)

IC50: 1.01E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair

Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM50242324(CHEMBL4072441)

IC50: 1.03E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair

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Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM50242323(CHEMBL4070917)

IC50: 1.04E+4nMAssay Description:Inhibition of horse serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair

Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)

IC50: 1.20E+4nMAssay Description:Inhibition of horse serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
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Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558935(CHEMBL4742170)

IC50: 1.26E+4nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM50242316(CHEMBL4103864)

IC50: 1.28E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair

Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM50242317(CHEMBL4085938)

IC50: 1.31E+4nMAssay Description:Concentration required to displace 50% of [3H]oxytocin from rat uterine receptor.More data for this Ligand-Target Pair

Acetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Malakand

Curated by ChEMBL

BDBM50242320(CHEMBL4065019)

IC50: 1.46E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair

Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM50242324(CHEMBL4072441)

IC50: 1.47E+4nMAssay Description:Inhibition of horse serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents Similars

Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM50242318(CHEMBL4098012)

IC50: 1.56E+4nMAssay Description:Inhibition of horse serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558941(CHEMBL4779734)

IC50: 1.62E+4nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM50242316(CHEMBL4103864)

IC50: 1.62E+4nMAssay Description:Inhibition of horse serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair

Cholinesterase(Equus caballus (Horse))
University Of Malakand

Curated by ChEMBL

BDBM50242320(CHEMBL4065019)

IC50: 1.81E+4nMAssay Description:Inhibition of horse serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558944(CHEMBL4764720)

IC50: 1.84E+4nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558949(CHEMBL4746020)

IC50: 2.00E+4nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558941(CHEMBL4779734)

IC50: 2.07E+4nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558942(CHEMBL4757410)

IC50: 2.13E+4nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558942(CHEMBL4757410)

IC50: 2.13E+4nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558946(CHEMBL4792260)

IC50: 2.19E+4nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558945(CHEMBL4776872)

IC50: 2.68E+4nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

Prostaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Malakand

Curated by ChEMBL

BDBM50558943(CHEMBL4777181)

IC50: 3.03E+4nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...More data for this Ligand-Target Pair

Prostaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Malakand

Curated by ChEMBL

BDBM50558934(CHEMBL4754218)

IC50: 3.09E+4nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...More data for this Ligand-Target Pair

Prostaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Malakand

Curated by ChEMBL

BDBM50558940(CHEMBL4750799)

IC50: 3.33E+4nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558949(CHEMBL4746020)

IC50: 3.60E+4nMAssay Description:Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...More data for this Ligand-Target Pair

Prostaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Malakand

Curated by ChEMBL

BDBM50558936(CHEMBL4794507)

IC50: 3.92E+4nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...More data for this Ligand-Target Pair

Prostaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Malakand

Curated by ChEMBL

BDBM50558939(CHEMBL4756619)

IC50: 3.93E+4nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Cytochrome c oxidase subunit 2(Homo sapiens (Human))
University Of Malakand

Curated by ChEMBL

BDBM50558944(CHEMBL4764720)

IC50: 3.95E+4nMAssay Description:Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...More data for this Ligand-Target Pair

Prostaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Malakand

Curated by ChEMBL

BDBM50558942(CHEMBL4757410)

IC50: 4.34E+4nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...More data for this Ligand-Target Pair